Synthetic mosquito repellent N, N-Diethyl-3-methylbenzamide (DEET) is widely used. Although it has a safety profile ,but number of reports on its toxicity against skin & nervous system like rashes, swelling, eye irritation, and worse problems including brain swelling in children, anaphylactic shock, low blood pressure. DEET must be used with caution in children as it cause dizziness and severely irritate the skin in long term use. Other effects are unpleasant odour, uncomfortable oily or sticky feeling. \r\nDue to these side effects herbal mosquito repellent are preferred over synthetic repellent. Different herbal mosquito repellent formulations using water soluble & removable base creams were prepared to study the mosquito repellent effect of garlic & cinnamon oil. Water removable base creams were better appreciated by the volunteers for their longer duration of action when applied on the skin. Water soluble bases cream were also appreciated by the volunteers but have shorter duration of action . Partitioning & non partitioning of the garlic & cinnamon oil among oily/ fatty ingredients of the water removable bases & soluble bases was attributed for slow and abrupt release of volatile oils from the preparation. Water removable creams containing cinnamon oil were better appreciated due to mild fragrance. The mosquito repellent activity of mixture of garlic & cinnamon oil containing water removable bases is high & prolong because cinnamon oil is used to mask the odor of garlic oil, but both of them have synergistic action on mosquito repellent.
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